IMSI (Intracytoplasmic Morphologically selected Sperm Injection)
IMSI (Intracytoplasmic Morphologically selected Sperm Injection) is a recently developed technique to further improve sperm selection criteria during ICSI (Intracytoplasmic Sperm Injection). Sperm may be evaluated using several techniques such as morphology, motility and sperm count. Sperm with morphologically abnormal shaped heads are associated with reduced fertility. Some morphologically abnormal head shapes such as “pinhead”, “tapered-head” or “multinucleated head” can be detected at relatively low magnification. Sperm that may appear normal at low magnification may have organelle defects or abnormalities on the sperm surface that can impede fertilization. These types of defects can be identified using the IMSI technique. IMSI uses technology that can magnify motile sperm at levels higher than 6000x. This technique has shown to be especially helpful in cases with severe male infertility.